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SAR407899 hydrochloride 是一种选择性,ATP 竞争性的ROCK 抑制剂,对人和大鼠ROCK2的Ki 值分别为 36 和 41 nM,对ROCK2的IC50值为 135 nM。
SAR407899 hydrochloride 是一种选择性,ATP 竞争性的ROCK 抑制剂,对人和大鼠ROCK2的Ki 值分别为 36 和 41 nM,对ROCK2的IC50值为 135 nM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 139 | 现货 | |
2 mg | ¥ 197 | 现货 | |
5 mg | ¥ 296 | 现货 | |
10 mg | ¥ 448 | 现货 | |
25 mg | ¥ 773 | 现货 | |
50 mg | ¥ 1,170 | 现货 | |
100 mg | ¥ 1,730 | 现货 | |
200 mg | ¥ 2,520 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 297 | 现货 |
产品描述 | SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively. |
靶点活性 | ROCK2:102 nM (IC50), ROCK1:276 nM (IC50) |
别名 | 6-(哌啶-4-氧基)异喹啉-1(2H)-酮盐酸盐 |
分子量 | 280.75 |
分子式 | C14H17ClN2O2 |
CAS No. | 923262-96-8 |
Smiles | Cl.O=c1[nH]ccc2cc(OC3CCNCC3)ccc12 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 45 mg/mL (160.28 mM), Sonication is recommended. H2O: 50 mg/mL (178.09 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
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